alison carey drexel
Read Dr. Carey's faculty highlight from the Women in Medicine and Science Committee. While there are medical treatments and supportive measures for infected infants, little is known about their initial immune response to pathogens. Drexel University College of Medicine Could Probiotics Help Prevent and Treat Infant Influenza?
Alison Carey was awarded the early career clinical scientist faculty award. I have also served as a mentor to several of the neonatology fellows at St. Christopher's Hospital. Alison J. Carey, MD, is an associate professor of pediatrics at Drexel University College of Medicine.Dr. ... Alison Carey, MD, Drexel University College of Medicine *Navigating the IRB. Kristie Cox. She worked in my lab for a year and also shadowed me in the NICU for a month.
/ Drexel University "Lung transcriptional unresponsiveness and loss of early influenza virus control in infected neonates is prevented by intranasal Lactobacillus rhamnosus GG" Kumova OK, Fike AJ, Thayer JL, Nguyen LT, Mell JC, Pascasio J, Stairiker C, Leon LG, Katsikis PD, Carey AJ PLoS Pathog. As we investigate the situation further, we propose two research goals: 1) Determine differences in gene activation in infected neonatal mouse lung cells versus adult mouse lung cells.
Georgetown University … The amount of virus in the pup's lungs is higher immediately after infection as compared to adults. HQ Phone: (215) 895-2000. Alison J. Carey Business Profile Core, Assistant Professor at Drexel University. Skip to main content
Email: a***@***.edu Get Email Address. This Career Development Award will serve as a driving force in Dr. Carey's success, providing the protected time and additional training required for this candidate to become an independent investigator.Influenza virus infection is particularly dangerous during the first few months of life. Last Updated: 2/5/2020 7:00 PM.
As a neonatologist, Alison Carey, M.D., sees many premature babies in the neonatal intensive care unit (NICU) who develop lung infections. / Drexel University: NIH 2019 R03 AI: Role of Gestational Age in T-Cell Receptor (TCR) Repertoire Development and Response to Infant Respiratory Viral Infection Carey, Alison J. However, up to this point, there have not been investigations into the use of intranasal probiotics for respiratory infections in infants. In order to study infant flu infection, we have established a model of neonatal flu infection in 3-day-old mice. Carey's research seeks to identify mechanisms and potential modifiable risk factors for infants' susceptibility to infections using animal models, Dr. Carey was awarded a biomedical research grant from the American Lung Association for her project, "Identification of the Toll-like Receptor Mediating Drexel University, College of Medicine, 2900 W. Queen Lane, Philadelphia, PA 19129, Carey, Alison J. Neonates face one of the highest rates of mortality and morbidity from infection. Katherine Innamorati Ph.D Candidate at Drexel University College of Medicine. Death and disability from influenza (flu) infection is highest in infants younger than 6 months, an age group not currently eligible for flu vaccines. / Drexel University: NIH 2014 K08 AI: Investigation of Neonatal Influenza Pathogenesis Carey, Alison J. We have established a clinically relevant model of neonatal influenza virus infection in 3-day-old neonatal mice in order to focus on both the adaptive and innate immune response to … This award is presented to an early or mid-career level faculty member who has already made a significant contribution to the field of biomedical, educational and/or health care research, as evidenced by extramural funding, scholarly productivity and research leadership. In addition to the proposed research, Dr. Carey has formulated a multi- pronged training plan, including: didactic courses, scientific meetings, clinical service, and a superb mentoring team. This early loss of viral control cannot be attributed to viral- specific T-cell immunity, as it is prior to the period when adults or neonates mount an immunodominant viral- specific CD8+ T-cell response in the lungs.
When I was completing my fellowship in neonatology, I was looking for an academic position where I could practice neonatology in a well-respected hospital and perform high-quality infectious disease research. Alison J. Carey, MD, a member of the faculty at Drexel University College of Medicine, has been nominated by department chairs and members of the Women in Medicine and Science Committee to be profiled for the WIMSC website. The Carey Lab seeks to identify mechanisms and potential modifiable risk factors for infants' susceptibility to infections using animal models, in vitro work and ex vivo studies on human cord blood. Alison has 4 jobs listed on their profile. The relative immaturity of the neonatal immune system has been attributed to decreased memory lymphocyte formation, delayed kinetics of a cytotoxic T cell (CTL) response, inadequate antigen presentation and defective neutrophil migration.To better understand the development of the neonatal immune system, our lab has established a neonatal mouse model of influenza infection in order to determine the phenotypic and functional characteristics of both the innate and adaptive immune system. Attaining more knowledge of neonatal immune responses is essential if we are to develop effective vaccines or therapeutics against influenza virus or other respiratory viruses. The mortality rate from influenza infection is highest in infants less thn the age of six months, which is currently an age group not eligible for the available influenza vaccine. Alison Carey Physician at Drexel University College of Medicine. According to the World Health Organization, 3.7 million neonates younger than 28 days of age died in 2010, and 37% of these deaths were due to infectious causes1.
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